Balasubramanian Narasimhan Prediction Analysis of Microarrays in Excel ******************************************* PAM (Prediction Analysis of Microarrays) is a technique for performing sample classification from gene expression data using the nearest shrunken centroid method. The method is described in the paper Diagnosis of multiple cancer types by shrunken centroids of gene expression, Proccedings of the National Academy of Sciences, 2002 99:6567-6572 (See http://www.pnas.org/cgi/reprint/99/10/6567). An R package of the software has been available for some time now and an Excel addin utilizing the RDCOM interface is undergoing final tests before release. In this talk, I will describe how we exploit the R DCOM server by Thomas Baier to provide a seamless integration to Excel, working around some known issues, and building a complete setup package.